You'll have a unique capacity to connect at the beginning of the week, whether it's with the zeitgeist of your destination, some fascinating locals or fellow travelers -- or, knowing you, all three. On Thursday or Friday, however, your adventures could be disrupted. Check the weather forecast and inquire at the front desk (or with someone in the know) about possible transportation delays, and be sure to build extra time into your schedule. You may see a great opportunity on the road this weekend. If you can share it with someone else, do: Your travel karma will reward you.